And Then

Phonetics and Phonology then , and then , and now 1

Phonetics attempts to describe and understand how speech is produced and perceived; phonology attempts to understand the patterning—in general, the behavior—of speech sounds in particular languages and in all languages. Is phonetics part of phonology? This straightforward question has received various answers at different points in the history of linguistics. In this paper I attempt to document...

Then and Now

Schizophrenia: Then and Now

EPS—Then and Now

"Slime" played a brief and spectacular role in the 19th century founded by the theory of primordial slime by Ernst Haeckel. However, that substance was never found and eventually abandoned. Further scientific attention slowly began in the 1930s referring to slime as a microbial product and then was inspired by "How bacteria stick" by Costerton et al. in 1978, and the matrix material was conside...

Fluoroquinolones: then and now.

Fluoroquinolones were discovered in the 1960s as a derivative of the antimalarial drug chloroquine. Over the past 40 years, many fluoroquinolones have been developed for use in human and veterinary medicine. As with all classes of antibiotics, resistance to fluoroquinolones is a serious concern, and multiple avenues for resistance are being investigated. Resistance-associated point mutations in...